Author - Dr. Vandana Narula, MBBS, MD (Obstetrics & Gynaecology)
Consultant - Infertility specialist in sector 43 Chandigarh

10 Common Reasons for IVF Failure

In-vitro fertilization or IVF provides a means towards parenthood to couples struggling with natural pregnancy. Although IVF is a successful, safe, and effective technique some couples may struggle with multiple IVF failures. According to Dr Vandana Narula, MBBS, MD (Obstetrics & Gynaecology), a lot of factors contribute to the success or failure of IVF. The best infertility specialist in sector 43 Chandigarh advises you to not lose hope and discuss the opportunities with your doctor.

10 Common Reasons for IVF Failure

The infertility & IVF specialist in Mohali gives the following common reasons for IVF failure:

1. Poor Sperm Quality

The quality of sperm determines the quality of the embryo. Men with certain medical conditions including azoospermia or diabetes may procedure poor quality and quantity of sperm. This can either hamper the development of the embryo or lead to an abnormal embryo.

2. Low Anti-Mullerian Hormone (AMH) Values

AMH is a hormone secreted by cells in the egg. A good level of AMH in the woman’s blood indicates good ovarian reserve. Women with low AMH values may procedure unhealthy eggs that may not be implanted.

3. Implantation Failure

Implantation failure is one of the common causes of IVF failures. It is usually caused by:

• A non-receptive uterus lining, thin lining, or lining affected by genital tuberculosis.
• Prevailing immunological conditions make the uterine environment hostile for the embryos.
• The endometrium has an inbuilt mechanism to reject poor-quality embryos.

4. Poor Quality of Eggs and Embryos

The quality of eggs plays a significant role in IVF failure. The quality of eggs is directly related to the age of a woman and her health. The human egg consists of 23 chromosomes. If any of these chromosomes are missing or arranged incorrectly, they can produce abnormal embryos.

A woman’s age also plays a key role in the egg quality. With advancing age, the eggs become less healthy and are prone to genetic abnormalities. This can make it difficult for them to be fertilized by sperm and lead to abnormal embryos.

5. Age of the Eggs

The oocytes or eggs are at the peak of fertilization between the ages of 24 to 35. Beyond 35 years, the quality of eggs begins to deteriorate making it difficult to get pregnant.

6. Ovarian Stimulation

Another factor governing the quality of eggs is ovarian stimulation. For good ovarian stimulation, an appropriate dose of hormonal injections needs to be administered. In some cases, even after providing the correct dose, the oocytes may not be stimulated. This produces poor-quality eggs.

7. Embryo Selection Method

Embryo selection is carried out by precise morphological examination under the microscope. A preimplantation genetic testing deselects abnormal embryos allowing only the genetically normal embryos to be selected for the transfer.

8. IVF Laboratory

Another less talked about is the IVF laboratory. The best infertility specialist in sector 43 Chandigarh tells us that the quality of the laboratory also affects your IVF success or failure. Embryos are sensitive to changes in oxygen, carbon dioxide concentration, humidity, pH, temperature, and light. Hence, trained embryologists are required to ensure the success of IVF.

9. Embryo Transfer

The type of embryo transfer also contributes to the success of IVF. A smooth embryo transfer with a fine catheter under ultrasound guidance improves your chances of pregnancy.

10. No response to Ovarian Stimulation

At times, low AMH levels coupled with diminished ovarian reserves create a condition wherein the women’s ovaries are not stimulated. This usually occurs in women with PCOS.

IVF failure is not the end of the world. Of course, you will be disappointed and upset. With, however, the best infertility & IVF specialist in Mohali, you can increase your chances of pregnancy. Visit Dr Vandana Narula at the Motherhood Hospitals today!